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Our Division’s Scholarship Well Represented at National Pediatric Endocrine Society Meeting

Dr. Eirene Alexandrou
Dr. Palmer
Dr. Catherina Pinnaro
Dr. Akhila Ramakrishna

Each year, pediatric endocrinologists from around the world attend the “PES Annual Meeting”, hosted by the Pediatric Endocrine Society (PES). The mission of the PES is primarily to “advance and promote the endocrine health and well being of children and adolescents“.  This year, several Division members submitted abstracts describing new research and advances for review by the PES. The following were selected for presentation at this years PES meeting, which was just held May 2-5 in Chicago.

  • Dr. Eirene Alexandrou: “Gonadotropin-Releasing Hormone Agonist Therapy in Patients Undergoing Dialysis – A Cautionary Tale!” – selected for a poster presentation. Co-author from our division on this work is Dr. Akhila Ramakrishna.
  • Dr. Ben Palmer: “Adolescent-driven Retrospective Glucose Data Self-Review is Associated with Improved Glycemic Control in Type 1 Diabetes Mellitus.” – selected for a poster presentation. Co-authors from our division on this work are Dr. Catherina Pinnaro, Dr, Andrew Norris, and Dr. Michael Tansey.
  • Dr. Catherina Pinnaro: “Influence of X Chromosome Parent-of-origin on Glycemia in Individuals with Turner syndrome” – selected for an prestigious oral presentation. Co-author from our division on this work is Dr. Andrew Norris.
  • Dr. Akhila Ramakrishna: “A rare case of a female with 47 XXY ovo-testicular DSD.” – selected for an prestigious oral presentation.

Congratulations to all for helping advance the field of Pediatric Endocrinology.

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Dr. Ramakrishna Named Co-Chair of National Adrenal Endocrine Disease Interest Group

Dr. Akhila Ramakrishna

Dr. Akhila Ramakrishna has been elected to co-chair the Pediatric Endocrine Society Special Interest Group focused on adrenal hormones. This group is a professional network who help guide dissemination and review of progress in the diagnostic workup and treatment of adrenal disorders in youth. This aligns well with Dr. Ramakrishna’s role as the lead endocrinologist in our DSD (differences in sex development) clinic, as adrenal disorders are a leading cause of DSD conditions. Her term in this position starts this month. Congratulations to Dr. Ramakrishna for her ongoing hard work in this area.

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Grand Rounds : When Does Overnutrition Become an Endocrine Problem?

Pediatric Grand Rounds Speakers: Feb 16, 2024

On February 16th, 2024, Drs. Kanner, Ramakrishna, and Parra Villasmil jointly delivered Pediatric Grand Rounds. Their talk was entitled “When Overnutrition Becomes an Endocrine Problem…Food for Thought“. They focused on the endocrine complications that can occur as a consequence of overweight and obesity in children and adolescents. Additionally, they touched on the practicalities of providing care to obese youth.

In the United States, nearly 1 in 5 children and adolescents are obese. In Iowa alone, over 50,000 youth are obese, per 2019 estimates (reference). Due to these high numbers, specialized obesity clinics are not a currently tenable solution. While most obese youth won’t develop endocrine complications, some may experience conditions such as type 2 diabetes, dyslipidemia, or polycystic ovarian syndrome.

Our Division accept referrals when these endocrine complications arise. Additionally, we welcome referrals for those rare cases where obesity is linked to endocrine conditions such as hypothyroidism or Cushing syndrome. Another reason for referral to endocrinology is when an obese adolescent and their family are prepared for the arduous process of bariatric surgery.

We extend our thanks to Drs. Kanner, Ramakrishna, and Parra Villasmil for sharing their expertise!

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DSD Clinic Opens

Dr. Akhila Ramakrishna

Dr. Ramakrishna from our division has worked diligently with with several other pediatric sub-specialties to create the regions first clinic for children with DSD (differences in sex development). DSD represent a collection of conditions whereby the usual processes of sexual development have not occurred in the usual fashion. The usual anatomic, functional, hormonal, and/or reproductive functions are altered, absent, or mixed. DSDs are often evident at or even before birth, but some forms are not diagnosed until adulthood. Dr. Ramakrishna has partnered with pediatric urologist Dr. Gina Lockwood and clinical psychologist Dr. Laura Fuller to create the Iowa Gender Multi-Specialty (iGeMS) clinic. The clinic works to maximize the physical and emotional health of youth with DSD, using a multidisciplinary approach. The clinic additionally is staffed by clinical geneticists, pediatric radiologists, with support from reproductive endocrinology and clinical pharmacy services. Referral and appointment requests can be made as outlined on Dr. Ramakrishna’s clinical webpage (link).

Some of the DSD clinic providers:
Dr. Lockwood, Dr. Ramakrishna, Dr. Fuller
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Drs. Alexandrou, Pinnaro, & Ramakrishna Pass Boards!

  • Dr. Eirene Alexandrou
  • Dr. Catherina Pinnaro
  • Dr. Akhila Ramakrishna

It takes years of training to become a pediatric endocrinologist, requiring at least a decade of studies after college. You could consider this to be the equivalent of completing the “26th grade”. The final step is to pass the Pediatric Endocrinology board exam. We are pleased to report that the three newest doctors in our Division have just passed their Board Exam. Congratulations to Drs. Alexandrou, Pinnaro, & Ramakrishna for becoming Board Certified Pediatric Endocrinologists. Their years of hard work and study have enabled them to become well qualified to diagnose and treat pediatric endocrine conditions.

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A Novel Approach that Might Prevent “Belly Fat”

Dr. Akhila Ramakrishna

Perhaps the worst place to gain fat is inside your abdomen. This type of fat is called visceral fat, and contribute to risk of cardiovascular disease, type 2 diabetes, and a host of related complications. Unfortunately, it is also a common place to gain fat. Dr. Ramakrishna has just published new research that has identified a potential new strategy to prevent visceral fat. She used two approaches in mice to reduce the amounts of a protein called PAPP-A. This was accomplished using a genetic and a neutralizing antibody approach respectively. These treatments reduced the amounts of visceral fat that the mice developed while on a high fa diet. Not only was the amount of visceral fat reduced, but the treatments helped prevent fatty liver. She published the work in the journal Endocrinology (link to paper). We look forward to further development of this approach.

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Announcing New Faculty: Akhila Ramakrishna, MD

Dr. Ramakrishna

We are pleased to announce that Dr. Akhila Ramakrishna is starting as a new pediatric endocrinologist in our division. She received her Medical Degree from the Armed Forces Medical College, then completed a residency in pediatrics at Case Western Reserve, and just completed a fellowship in pediatric endocrinology at the prestigious Mayo Clinic. She has published expertise in the area of thyroid dysfunction (link) and has studied rodent models of obesity as a fellow as well. In clinic, her practice will include general pediatric endocrinology and diabetes, as well as gender-related endocrine care, obesity-related endocrine care especially regarding bariatric surgery in adolescents, and outreach pediatric endocrine services in Cedar Falls.