Pancreatitis often leads to hyperglycemia. However, there have been major limitations in understanding the involved pathophysiology. Several collaborators at the University of Iowa have now created a model to help understand the process. The research team found that cerulein injections led to pancretitis with elevated amylase and lipase. Acute accompanied the acute pancreatitis, with both impaired insulin levels and evidence of insulin resistance. Glucose tolerance normalized by 3 months. The research team included our Dr. Andrew Norris, but also pediatric gastroenterologist Aliye Uc and researchers and faculty from the Department of Anatomy and Cell Biology.